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Penam

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Penam
Wikipedia EN

Penams are the primary skeleton structures that define the penicillin subclass of the broader β-lactam family of antibiotics and related compounds. They are bicyclic ring systems containing a β-lactam moiety fused with a five-member thiazolidine ring. Due to ring strain and limitations on amide resonance, the structure is unstable and highly susceptible to catalytic cleavage at the amide bond. Benzylpenicillin is the natural product parent that contains the penam structure.

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10 articles first seen 05.05.2026 last seen 01.09.2026
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