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Traumatické poranění mozku, také intrakraniální poranění nebo jednoduše poranění hlavy, je poranění mozku způsobené fyzickým traumatem, které poničí mozek. TBI je jednou ze dvou podmnožin získaných poranění mozku. TBI může vzniknout uzavřeným poraněním hlavy nebo penetrujícím poraněním hlavy. Poničeny jsou různé části mozku, mozkové hemisféry, cerebellum (mozeček) a nebo mozkový kmen.

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